Intramuscular dimethyl trisulfide: Efficacy in a large swine model of acute severe cyanide toxicity

BACKGROUND: Cyanide is a deadly compound used as a terrorist agent. Current FDA approved antidotes require intravenous administration, limiting their utility in a mass casualty scenario. Dimethyl trisulfide (DMTS), a sulfur-based molecule, binds cyanide converting it to the less toxic by-product thi...

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Udgivet i:Clin Toxicol (Phila)
Main Authors: Hendry-Hofer, Tara B., Witeof, Alyssa E., Lippner, Dennean S., Ng, Patrick C., Mahon, Sari B., Brenner, Matthew, Rockwood, Gary A., Bebarta, Vikhyat S.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451663/
https://ncbi.nlm.nih.gov/pubmed/30306816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15563650.2018.1511800
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