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Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo

Treatment with PPARγ agonists in vivo improves human adipocyte metabolism, but the cellular mechanisms and possible depot differences in responsiveness to their effects are poorly understood. To examine the ex vivo metabolic effects of rosiglitazone (Rosi), we cultured explants of human visceral (om...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Lee, Mi-Jeong, Jash, Sukanta, Jones, Jessica E. C., Puri, Vishwajeet, Fried, Susan K.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446708/
https://ncbi.nlm.nih.gov/pubmed/30782959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M091173
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