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Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo

Treatment with PPARγ agonists in vivo improves human adipocyte metabolism, but the cellular mechanisms and possible depot differences in responsiveness to their effects are poorly understood. To examine the ex vivo metabolic effects of rosiglitazone (Rosi), we cultured explants of human visceral (om...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Lee, Mi-Jeong, Jash, Sukanta, Jones, Jessica E. C., Puri, Vishwajeet, Fried, Susan K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446708/
https://ncbi.nlm.nih.gov/pubmed/30782959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M091173
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