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Evaluation of A Novel Pb-203-Labeled Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide for Melanoma Targeting

The purpose of this study is to examine the melanocortin-1 receptor (MC1R) targeting and specificity of (203)Pb-DOTA-GGNle-CycMSH(hex) in melanoma cells and tumors to facilitate its potential therapeutic application when labeled with (212)Pb. The melanocortin-1 receptor (MC1R)-specific targeting and...

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Yang, Jianquan, Xu, Jingli, Cheuy, Lina, Gonzalez, Rene, Fisher, Darrell R., Miao, Yubin
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443429/
https://ncbi.nlm.nih.gov/pubmed/30763112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00025
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