POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

BACKGROUND: Hyper-activation of TGF-β signaling is critically involved in progression of hepatocellular carcinoma (HCC). However, the events that contribute to the dysregulation of TGF-β pathway in HCC, especially at the post-translational level, are not well understood. METHODS: Associations of deu...

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Vydáno v:EBioMedicine
Hlavní autoři: Wang, Boshi, Xu, Xiaoli, Yang, Zhaojuan, Zhang, Li, Liu, Yun, Ma, Aihui, Xu, Guiqin, Tang, Ming, Jing, Tiantian, Wu, Lin, Liu, Yongzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441868/
https://ncbi.nlm.nih.gov/pubmed/30745168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.058
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