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Altered Pharmacokinetics of Combined Oral Contraceptives in Obesity – Multi-Study Assessment

OBJECTIVES: To evaluate the pharmacokinetics (PK) of levonorgestrel-containing combined oral contraceptives (COCs) in obese women. STUDY DESIGN: We pooled and reanalyzed data from 89 women with different BMI categories from four clinical studies. The levonorgestrel (LNG) and ethinyl estradiol (EE) P...

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Bibliographic Details
Published in:Contraception
Main Authors: Luo, Dandan, Westhoff, Carolyn L., Edelman, Alison B., Natavio, Melissa, Stanczyk, Frank Z., Jusko, William J.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441376/
https://ncbi.nlm.nih.gov/pubmed/30684471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2018.12.009
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