15-keto-prostaglandin E(2) activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection

Cryptococcus neoformans is one of the leading causes of invasive fungal infection in humans worldwide. C. neoformans uses macrophages as a proliferative niche to increase infective burden and avoid immune surveillance. However, the specific mechanisms by which C. neoformans manipulates host immunity...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Evans, Robert J., Pline, Katherine, Loynes, Catherine A., Needs, Sarah, Aldrovandi, Maceler, Tiefenbach, Jens, Bielska, Ewa, Rubino, Rachel E., Nicol, Christopher J., May, Robin C., Krause, Henry M., O’Donnell, Valerie B., Renshaw, Stephen A., Johnston, Simon A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438442/
https://ncbi.nlm.nih.gov/pubmed/30921435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007597
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars