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Mitochondria transfer from mesenchymal stem cells structurally and functionally repairs renal proximal tubular epithelial cells in diabetic nephropathy in vivo

The underlying therapeutic mechanism of renal tubular epithelium repair of diabetic nephropathy (DN) by bone marrow-derived mesenchymal stem cells (BM-MSCs) has not been fully elucidated. Recently, mitochondria (Mt) transfer was reported as a novel action of BM-MSCs to rescue injured cells. We inves...

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Vydáno v:Sci Rep
Hlavní autoři: Konari, Naoto, Nagaishi, Kanna, Kikuchi, Shin, Fujimiya, Mineko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435708/
https://ncbi.nlm.nih.gov/pubmed/30914727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40163-y
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