Wird geladen...

In Silico Molecular Docking and In Vivo Validation with Caenorhabditis elegans to Discover Molecular Initiating Events in Adverse Outcome Pathway Framework: Case Study on Endocrine-Disrupting Chemicals with Estrogen and Androgen Receptors

Molecular docking is used to analyze structural complexes of a target with its ligand for understanding the chemical and structural basis of target specificity. This method has the potential to be applied for discovering molecular initiating events (MIEs) in the Adverse Outcome Pathway framework. In...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Jeong, Jaeseong, Kim, Hunbeen, Choi, Jinhee
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429066/
https://ncbi.nlm.nih.gov/pubmed/30857347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051209
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!