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Transcriptome and epigenome landscape of human cortical development modeled in brain organoids
Genes implicated in neuropsychiatric disorders are active in human fetal brain, yet difficult to study in a longitudinal fashion. We demonstrate that organoids from human pluripotent cells model cerebral cortical development on the molecular level before 16 weeks post-conception. A multi-omics analy...
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| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426303/ https://ncbi.nlm.nih.gov/pubmed/30545853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat6720 |
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