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Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

BACKGROUND: Senescent cells exert a significant influence over their surrounding cellular environment. Senescent chondrocytes (SnChos) were found to be accumulated in degenerated cartilage present in joints affected by osteoarthritis. The influence of SnChos on exogenously transplanted stem cells ha...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Cao, Xu, Luo, Pan, Huang, Junjie, Liang, Chi, He, Jinshen, Wang, Zili, Shan, Dongyong, Peng, Cheng, Wu, Song
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416972/
https://ncbi.nlm.nih.gov/pubmed/30867061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1193-1
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