Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

BACKGROUND: Senescent cells exert a significant influence over their surrounding cellular environment. Senescent chondrocytes (SnChos) were found to be accumulated in degenerated cartilage present in joints affected by osteoarthritis. The influence of SnChos on exogenously transplanted stem cells ha...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Cao, Xu, Luo, Pan, Huang, Junjie, Liang, Chi, He, Jinshen, Wang, Zili, Shan, Dongyong, Peng, Cheng, Wu, Song
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416972/
https://ncbi.nlm.nih.gov/pubmed/30867061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1193-1
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