Targeting late-stage non-small cell lung cancer with a combination of DNT cellular therapy and PD-1 checkpoint blockade

BACKGROUND: Though immune checkpoint blockade (ICB) against PD-1 has shown success in the treatment of lung cancer, not all patients respond. We have previously shown that adoptive transfer of double negative T (DNT) cells expanded from healthy donors can target leukemia but their role in treating e...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Fang, Linan, Ly, Dalam, Wang, Si-si, Lee, Jong Bok, Kang, Hyeonjeong, Xu, Hao, Yao, Junlin, Tsao, Ming-sound, Liu, Wei, Zhang, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413451/
https://ncbi.nlm.nih.gov/pubmed/30857561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1126-y
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