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Quality Screening of Incorrectly Folded Soluble Aggregates from Functional Recombinant Proteins

Solubility is the prime criterion for determining the quality of recombinant proteins, yet it often fails to represent functional activity due to the involvement of non-functional, misfolded, soluble aggregates, which compromise the quality of recombinant proteins. However, guidelines for the qualit...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kwon, Soon Bin, Yu, Ji Eun, Kim, Jihoon, Oh, Hana, Park, Chan, Lee, Jinhee, Seong, Baik L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413200/
https://ncbi.nlm.nih.gov/pubmed/30791505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040907
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