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Selection of self-priming molecular replicators

Self-priming amplification of oligonucleotides is possible based on foldback of 3′ ends, self-priming, and concatemerization, especially in the presence of phosphorothioate linkages. Such a simple replicative mechanism may have led to the accumulation of specific replicators at or near the origin of...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Park, Daechan, Ellington, Andrew D, Jung, Cheulhee
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412129/
https://ncbi.nlm.nih.gov/pubmed/30698805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz044
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