Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation

OBJECTIVES: To investigate the protective effect of ginsenoside Rg1 on relieving sepsis-induced lung inflammation and injury in vivo and in vitro. METHODS: Cultured human pulmonary epithelial cell line A549 was challenged with LPS to induce cell injury, and CLP mouse model was generated to mimic cli...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Wang, Qian-Lu, Yang, Lei, Peng, Yue, Gao, Min, Yang, Ming-Shi, Xing, Wei, Xiao, Xian-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409002/
https://ncbi.nlm.nih.gov/pubmed/30918470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6453296
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