Pharmacokinetics and Pharmacodynamics of Liposomal Chemophototherapy with Short Drug-Light Intervals

Chemophototherapy (CPT) merges photodynamic therapy with chemotherapy and can substantially enhance drug delivery. Using a singular liposomal formulation for CPT, we describe a semi-mechanistic pharmacokinetic-pharmacodynamic (PK/PD) model to investigate observed antitumor effects. Long-circulating,...

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Bibliografske podrobnosti
izdano v:J Control Release
Main Authors: Luo, Dandan, Carter, Kevin A, Molins, Emilie A.G., Straubinger, Ninfa L., Geng, Jumin, Shao, Shuai, Jusko, William J., Straubinger, Robert M., Lovell, Jonathan F.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399029/
https://ncbi.nlm.nih.gov/pubmed/30684512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.01.030
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