Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury

BACKGROUND: Lonomia obliqua venom is nephrotoxic and acute kidney injury (AKI) is the main cause of death among envenomed victims. Mechanism underlying L. obliqua-induced AKI involves renal hypoperfusion, inflammation, tubular necrosis and loss of glomerular filtration and tubular reabsorption capac...

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Bibliographic Details
Published in:PLoS Negl Trop Dis
Main Authors: Berger, Markus, de Moraes, João Alfredo, Beys-da-Silva, Walter Orlando, Santi, Lucélia, Terraciano, Paula Barros, Driemeier, David, Cirne-Lima, Elizabeth Obino, Passos, Eduardo Pandolfi, Vieira, Maria Aparecida Ribeiro, Barja-Fidalgo, Thereza Christina, Guimarães, Jorge Almeida
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392336/
https://ncbi.nlm.nih.gov/pubmed/30763408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007197
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