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A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats

A recombinant humanized anticocaine monoclonal antibody, h2E2, has shown potential in the preclinical phases for the treatment of cocaine abuse. The standard tests for cocaine usage are the detection of benzoylecgonine (BE) and cocaine in the urine. This includes workplace drug screens as well as in...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Marckel, Jordan A., Wetzel, Hanna N., Amlal, Sihame, Amlal, Hassane, Norman, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367686/
https://ncbi.nlm.nih.gov/pubmed/30578276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.118.083857
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