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Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains
Most variants associated with complex phenotypes in genome-wide association studies (GWAS) do not directly index coding changes affecting protein structure. Instead they are hypothesized to influence gene regulation, with common variants associated with disease being enriched in regulatory domains i...
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| 出版年: | Mol Brain |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348673/ https://ncbi.nlm.nih.gov/pubmed/30691483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0429-4 |
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