Lipid Uptake by Alveolar Macrophages Drives Fibrotic Responses to Silica Dust

Silicosis is a common occupational disease and represents a significant contributor to respiratory morbidity and mortality worldwide. Lipid-laden macrophages, or foam cells, are observed in the lungs of patients with silicosis but the mechanisms mediating their formation remain poorly understood. In...

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Publicat a:Sci Rep
Autors principals: Hou, Xiaomin, Summer, Ross, Chen, Ziying, Tian, Ying, Ma, Jingjing, Cui, Jie, Hao, Xiaohui, Guo, Lingli, Xu, Hong, Wang, Hongli, Liu, Heliang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344530/
https://ncbi.nlm.nih.gov/pubmed/30674959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36875-2
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