Self-derived structure-disrupting peptides targeting methionine aminopeptidase in pathogenic bacteria: a new strategy to generate antimicrobial peptides

Bacterial infection is one of the leading causes of death in young, elderly, and immune-compromised patients. The rapid spread of multi-drug–resistant (MDR) bacteria is a global health emergency and there is a lack of new drugs to control MDR pathogens. We describe a heretofore-unexplored discovery...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Zhan, Jian, Jia, Husen, Semchenko, Evgeny A., Bian, Yunqiang, Zhou, Amy M., Li, Zhixiu, Yang, Yuedong, Wang, Jihua, Sarkar, Sohinee, Totsika, Makrina, Blanchard, Helen, Jen, Freda E.-C., Ye, Qizhuang, Haselhorst, Thomas, Jennings, Michael P., Seib, Kate L., Zhou, Yaoqi
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338635/
https://ncbi.nlm.nih.gov/pubmed/30260702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700613RR
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