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ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease characterized by motor neuron cell death. However, not all motor neurons are equally susceptible. Most of what we know about the surviving motor neurons comes from gene expression profiling; less is known about the...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Osking, Zachary, Ayers, Jacob I., Hildebrandt, Ryan, Skruber, Kristen, Brown, Hilda, Ryu, Daniel, Eukovich, Amanda R., Golde, Todd E., Borchelt, David R., Read, Tracy-Ann, Vitriol, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327879/
https://ncbi.nlm.nih.gov/pubmed/30639851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.12.026
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