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Deep Profiling of the Aggregated Proteome in Alzheimer’s Disease: From Pathology to Disease Mechanisms

Hallmarks of Alzheimer’s disease (AD), a progressive neurodegenerative disease causing dementia, include protein aggregates such as amyloid beta plaques and tau neurofibrillary tangles in a patient’s brain. Understanding the complete composition and structure of protein aggregates in AD can shed lig...

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Bibliographic Details
Published in:Proteomes
Main Authors: Lutz, Brianna M., Peng, Junmin
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6313861/
https://ncbi.nlm.nih.gov/pubmed/30424485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/proteomes6040046
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