Elevation of extracellular osmolarity improves signs of myotonia congenita in vitro: a preclinical animal study

KEY POINTS: During myotonia congenita, reduced chloride (Cl(−)) conductance results in impaired muscle relaxation and increased muscle stiffness after forceful voluntary contraction. Repetitive contraction of myotonic muscle decreases or even abolishes myotonic muscle stiffness, a phenomenon called...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Hoppe, Kerstin, Chaiklieng, Sunisa, Lehmann‐Horn, Frank, Jurkat‐Rott, Karin, Wearing, Scott, Klingler, Werner
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Muscle
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312412/
https://ncbi.nlm.nih.gov/pubmed/30284249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276528
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