Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

Orexins (OX), also known as hypocretins, are excitatory neuropeptides with well-described roles in regulation of wakefulness, arousal, energy homeostasis, and anxiety. An additional and recently recognized role of OX is modulation of fear responses. We studied the OX neurons of the perifornical hypo...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Dustrude, Erik T., Caliman, Izabela F., Bernabe, Cristian S., Fitz, Stephanie D., Grafe, Laura A., Bhatnagar, Seema, Bonaventure, Pascal, Johnson, Philip L., Molosh, Andrei I., Shekhar, Anantha
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305451/
https://ncbi.nlm.nih.gov/pubmed/30618563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00934
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