Fingolimod enhances the efficacy of delayed alteplase administration in acute ischemic stroke by promoting anterograde reperfusion and retrograde collateral flow

OBJECTIVE: The present study was undertaken to determine the efficacy of coadministration of fingolimod with alteplase in acute ischemic stroke patients in a delayed time window. METHODS: This was a prospective, randomized, open‐label, blinded endpoint clinical trial, enrolling patients with interna...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Tian, De‐Cai, Shi, Kaibin, Zhu, Zilong, Yao, Jia, Yang, Xiaoxia, Su, Lei, Zhang, Sheng, Zhang, Meixia, Gonzales, Rayna J., Liu, Qiang, Huang, DeRen, Waters, Michael F., Sheth, Kevin N., Ducruet, Andrew F., Fu, Ying, Lou, Min, Shi, Fu‐Dong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282815/
https://ncbi.nlm.nih.gov/pubmed/30295338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25352
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