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Design, Synthesis, and Cytotoxicity of 5-Fluoro-2-methyl-6-(4-aryl-piperazin-1-yl) Benzoxazoles

To design new compounds suitable as starting points for anticancer drug development, we have synthesized a novel series of benzoxazoles with pharmaceutically advantageous piperazine and fluorine moieties attached to them. The newly synthesized benzoxazoles and their corresponding precursors were eva...

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Bibliographic Details
Published in:Molecules
Main Authors: Al-Harthy, Thuraya, Zoghaib, Wajdi Michel, Pflüger, Maren, Schöpel, Miriam, Önder, Kamil, Reitsammer, Maria, Hundsberger, Harald, Stoll, Raphael, Abdel-Jalil, Raid
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274350/
https://ncbi.nlm.nih.gov/pubmed/27689973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101290
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