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Synthesis and Cytotoxic Activity Evaluation of Novel Arylpiperazine Derivatives on Human Prostate Cancer Cell Lines

A series of novel arylpiperazine derivatives was synthesized. The in vitro cytotoxic activities of all synthesized compounds against three human prostate cancer cell lines (PC-3, LNCaP, and DU145) were evaluated by a CCK-8 assay. Compounds 9 and 15 exhibited strong cytotoxic activities against LNCaP...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Hong, Liang, Xue, Xu, Fang, Xu, Bingbing, He, Xuelan, Huang, Biyun, Yuan, Mu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271825/
https://ncbi.nlm.nih.gov/pubmed/25120056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190812048
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