A carregar...
Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands
A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinities with K(i) values in the nanomolar range. JM...
Na minha lista:
| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6270614/ https://ncbi.nlm.nih.gov/pubmed/23558540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18043972 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|