Mitigating Human IAPP Amyloidogenesis in Vivo with Chiral Silica Nanoribbons

Amyloid fibrils generally display chirality, a feature which has rarely been exploited in the development of therapeutics against amyloid diseases. Here we report, for the first time, the use of mesoscopic chiral silica nanoribbons against the in vivo amyloidogenesis of human islet amyloid polypepti...

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Detalhes bibliográficos
Publicado no:Small
Main Authors: Faridi, Ava, Sun, Yunxiang, Okazaki, Yutaka, Peng, Guotao, Gao, Jie, Kakinen, Aleksandr, Faridi, Pouya, Zhao, Mei, Javed, Ibrahim, Purcell, Anthony W., Davis, Thomas P., Lin, Sijie, Oda, Reiko, Ding, Feng, Ke, Pu Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263833/
https://ncbi.nlm.nih.gov/pubmed/30369028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201802825
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