Anti-fibrosis Effect of Novel Oridonin Analog CYD0618 via Suppression of the NF-κΒ Pathway

BACKGROUND: Liver fibrosis is characterized as excessive deposition of the extracellular matrix (ECM) proteins, primarily by activated hepatic stellate cells (HSCs). NF-κB has been reported as one of major mediators of HSC activation. Previously, our team reported that oridonin exhibited anti-hepati...

Full description

Saved in:
Bibliographic Details
Published in:J Surg Res
Main Authors: Cummins, Claire B., Wang, Xiaofu, Xu, Jimin, Hughes, Byron D., Ding, Ye, Chen, Haiying, Zhou, Jia, Radhakrishnan, Ravi S.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251495/
https://ncbi.nlm.nih.gov/pubmed/30463731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2018.06.040
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items