A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking

O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans, dysregulation of O-GlcNAcylation occurs in a wide range of diseases, including cancer, diabetes, and neurodegeneration. Since its discovery more than 3...

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Publicat a:Front Endocrinol (Lausanne)
Autors principals: Cox, Nathan J., Luo, Peter M., Smith, Timothy J., Bisnett, Brittany J., Soderblom, Erik J., Boyce, Michael
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Endocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232944/
https://ncbi.nlm.nih.gov/pubmed/30459710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00606
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