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A rapamycin derivative, biolimus, preferentially activates autophagy in vascular smooth muscle cells
Although rapamycin is a well-known conformational inhibitor of mTORC1, it is now widely used for treating arterial restenosis. Various rapamycin analogues (rapalogue) have been made for applying to drug-eluting stents. Here we show that two major rapalogues, everolimus and biolimus, exert a differen...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224423/ https://ncbi.nlm.nih.gov/pubmed/30410117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34877-8 |
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