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Analysis of the Binding of Aripiprazole to Human Serum Albumin: The Importance of a Chloro-Group in the Chemical Structure
[Image: see text] Aripiprazole (ARP), a quinolinone derivative, is an atypical antipsychotic drug that is used in the treatment of schizophrenia. ARP has an extensive distribution and more than 99% of the ARP and dehydro-ARP, the main active metabolite, is bound to plasma proteins. However, informat...
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| Publicado en: | ACS Omega |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2018
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217653/ https://ncbi.nlm.nih.gov/pubmed/30411049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b02057 |
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