ACTR-55. TUMOR VOLUME AS A PREDICTOR OF RESPONSE TO ANTI-EGFR ADC ABT-414

BACKGROUND: Adverse biophysical factors (abnormal vessels and increased interstitial pressure) are increased in larger brain tumors, which negatively impacts penetration of antibody drug conjugates (ADC). The tumour-specific anti-EGFR ADC, depatuxizumab mafadotin (depatux-m), demonstrated encouragin...

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Vydáno v:Neuro Oncol
Hlavní autoři: Gan, Hui, Seow, Aidan, Lau, Eddie, Sze-Ting, Lee, Ameratunga, Malaka, Perchyonok, Yuliya, Cao, Diana, Rigopoulos, Angela, Lee, Ho-Jin, Gomez, Erica, Maag, David, Scott, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216445/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.087
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