Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells

Early secretion of IL-12 by mouse dendritic cells (DCs) instructs T cells to make IFN-γ. However, only activated, but not naive T cells are able to license DCs for IL-12 production. We hypothesized that it might be due to different levels of CD40L expression on the surface of these cells, as CD40 si...

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Vydáno v:J Immunol
Hlavní autoři: Abdi, Kaveh, Laky, Karen, Padhan, Kartika, Petrovas, Constantinos, Skinner, Jeff, Kabat, Juraj, Dorward, David W., Brzostowski, Joseph, Long, Eric O., Trinchieri, Giorgio, Varma, Rajat
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2018
Témata:
Cutting Edge
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215252/
https://ncbi.nlm.nih.gov/pubmed/30315139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800721
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