Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels

Platelets, cells central to hemostasis and thrombosis, are formed from parent cell megakaryocytes. Although the process is highly efficient in vivo, our ability to generate them in vitro is still remarkably inefficient. We proposed that greater understanding of the process in vivo is needed and used...

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Udgivet i:Life Sci Alliance
Main Authors: Brown, Edward, Carlin, Leo M, Nerlov, Claus, Lo Celso, Cristina, Poole, Alastair W
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2018
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211653/
https://ncbi.nlm.nih.gov/pubmed/30393781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800061
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