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Antagonistic pleiotropy for carbon use is rare in new mutations

Pleiotropic effects of mutations underlie diverse biological phenomena such as ageing and specialization. In particular, antagonistic pleiotropy (“AP”: when a mutation has opposite fitness effects in different environments) generates tradeoffs, which may constrain adaptation. Models of adaptation ty...

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Detalhes bibliográficos
Publicado no:Evolution
Main Authors: Sane, Mrudula, Miranda, Joshua John, Agashe, Deepa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203952/
https://ncbi.nlm.nih.gov/pubmed/30095155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/evo.13569
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