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The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis

Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a surface protein on T cells, that has an inhibitory effect on the host immune reaction and prevents overreaction of the immune system. Because the functional single-nucleotide polymorphism (SNP) rs231775 of the CTLA-4 gene is associated with a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mewes, Caspar, Büttner, Benedikt, Hinz, José, Alpert, Ayelet, Popov, Aron Frederik, Ghadimi, Michael, Beissbarth, Tim, Tzvetkov, Mladen, Shen-Orr, Shai, Bergmann, Ingo, Mansur, Ashham
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181961/
https://ncbi.nlm.nih.gov/pubmed/30310101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33246-9
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