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Metabolic regulation and glucose sensitivity of cortical radial glial cells

The primary stem cells of the cerebral cortex are the radial glial cells (RGCs), and disturbances in their operation lead to myriad brain disorders in all mammals from mice to humans. Here, we found in mice that maternal gestational obesity and hyperglycemia can impair the maturation of RGC fibers a...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Rash, Brian G., Micali, Nicola, Huttner, Anita J., Morozov, Yury M., Horvath, Tamas L., Rakic, Pasko
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176632/
https://ncbi.nlm.nih.gov/pubmed/30224493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808066115
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