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M1 Macrophage Polarization Is Dependent on TRPC1-Mediated Calcium Entry
Macrophage plasticity is essential for innate immunity, but in-depth signaling mechanism(s) regulating their functional phenotypes are ill-defined. Here we report that interferon (IFN) γ priming of naive macrophages induces store-mediated Ca(2+) entry and inhibition of Ca(2+) entry impairs polarizat...
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| Publicado no: | iScience |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174824/ https://ncbi.nlm.nih.gov/pubmed/30293012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.09.014 |
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