Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

BACKGROUND: The recurrence score based on the 21-gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy for most patients, who have a midrange score...

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Vydáno v:N Engl J Med
Hlavní autoři: Sparano, Joseph A., Gray, Robert J., Makower, Della F., Pritchard, Kathleen I., Albain, Kathy S., Hayes, Daniel F., Geyer, Charles E., Dees, Elizabeth C., Goetz, Matthew P., Olson, John A., Lively, Tracy, Badve, Sunil S., Saphner, Thomas J., Wagner, Lynne I., Whelan, Timothy J., Ellis, Matthew J., Paik, Soonmyung, Wood, William C., Ravdin, Peter M., Keane, Maccon M., Moreno, Henry L. Gomez, Reddy, Pavan S., Goggins, Timothy F., Mayer, Ingrid A., Brufsky, Adam M., Toppmeyer, Deborah L., Kaklamani, Virginia G., Berenberg, Jeffrey L., Abrams, Jeffrey, Sledge, George W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172658/
https://ncbi.nlm.nih.gov/pubmed/29860917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1804710
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