Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication

In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous bupivacaine, followed by an intravenous injection of adr...

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Veröffentlicht in:PLoS One
Hauptverfasser: Li, Jun, Duan, Ran, Zhang, Yingying, Zhao, Xin, Cheng, Yanxin, Chen, Yongxue, Yuan, Jinge, Li, Hong, Zhang, Jianping, Chu, Li, Xia, Dengyun, Zhao, Senming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166930/
https://ncbi.nlm.nih.gov/pubmed/30273351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203602
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