IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD

Interferon-gamma (IFN-γ) is a pleiotropic cytokine that exerts important functions in inflammation, infectious diseases, and cancer. The large GTPase human guanylate-binding protein 1 (GBP-1) is among the most strongly IFN-γ-induced cellular proteins. Previously, it has been shown that GBP-1 mediate...

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Vydáno v:Biochem J
Hlavní autoři: Unterer, Bea, Wiesmann, Veit, Gunasekaran, Mekala, Sticht, Heinrich, Tenkerian, Clara, Behrens, Jürgen, Leone, Marina, Engel, Felix B., Britzen-Laurent, Nathalie, Naschberger, Elisabeth, Wittenberg, Thomas, Stürzl, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156764/
https://ncbi.nlm.nih.gov/pubmed/30120107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180123
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