The Antiproliferative Effect of Cyclodipeptides from Pseudomonas aeruginosa PAO1 on HeLa Cells Involves Inhibition of Phosphorylation of Akt and S6k Kinases

Pseudomonas aeruginosa PAO1, a potential pathogen of plants and animals, produces the cyclodipeptides cyclo(l-Pro-l-Tyr), cyclo(l-Pro-l-Phe), and cyclo(l-Pro-l-Val) (PAO1-CDPs), whose effects have been implicated in inhibition of human tumor cell line proliferation. Our purpose was to investigate in...

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Publié dans:Molecules
Auteurs principaux: Hernández-Padilla, Laura, Vázquez-Rivera, Dolores, Sánchez-Briones, Luis A., Díaz-Pérez, Alma L., Moreno-Rodríguez, José, Moreno-Eutimio, Mario A., Meza-Carmen, Victor, Reyes-De la Cruz, Homero, Campos-García, Jesús
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152764/
https://ncbi.nlm.nih.gov/pubmed/28632179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22061024
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