Calpain2 mediates Rab5-driven focal adhesion disassembly and cell migration

The early endosome protein Rab5 was recently shown to promote cell migration by enhancing focal adhesion disassembly through mechanisms that remain elusive. Focal adhesion disassembly is associated to proteolysis of talin, in a process that requires calpain2. Since calpain2 has been found at vesicle...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Mendoza, Pablo A., Silva, Patricio, Díaz, Jorge, Arriagada, Cecilia, Canales, Jimena, Cerda, Oscar, Torres, Vicente A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149462/
https://ncbi.nlm.nih.gov/pubmed/29099266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2017.1377388
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