Association of ERBB Mutations With Clinical Outcomes of Afatinib- or Erlotinib-Treated Patients With Lung Squamous Cell Carcinoma: Secondary Analysis of the LUX-Lung 8 Randomized Clinical Trial

IMPORTANCE: Treatment choice for lung squamous cell carcinoma could be aided by identifying predictive biomarkers. OBJECTIVE: To assess whether patient outcomes in the LUX-Lung 8 trial were associated with ERBB gene family member aberrations in tumor specimens. DESIGN, SETTING, AND PARTICIPANTS: Ad...

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Detaylı Bibliyografya
Yayımlandı:JAMA Oncol
Asıl Yazarlar: Goss, Glenwood D., Felip, Enriqueta, Cobo, Manuel, Lu, Shun, Syrigos, Konstantinos, Lee, Ki Hyeong, Göker, Erdem, Georgoulias, Vassilis, Li, Wei, Guclu, Salih, Isla, Dolores, Min, Young Joo, Morabito, Alessandro, Ardizzoni, Andrea, Gadgeel, Shirish M., Fülöp, Andrea, Bühnemann, Claudia, Gibson, Neil, Krämer, Nicole, Solca, Flavio, Cseh, Agnieszka, Ehrnrooth, Eva, Soria, Jean-Charles
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Medical Association 2018
Konular:
Original Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143014/
https://ncbi.nlm.nih.gov/pubmed/29902295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.0775
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