Diminished TLR2-TLR9 mediated CD4+ T cell responses are associated with increased inflammation in intraocular tuberculosis

Intraocular tuberculosis (IOTB) is amongst the leading causes of uveitis in tropical countries. Despite reports on involvement of proinflammatory cytokines, studies on innate immune responses in disease pathogenesis are lacking. Reports from animal models and patients with pulmonary tuberculosis ind...

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Vydáno v:Sci Rep
Hlavní autoři: Sharma, Ravi Kumar, Sharma, Jyoti, Khan, Zafar K., Pattekar, Ajinkya, Gupta, Vishali, Bansal, Reema, Sharma, Kusum, Aggarwal, Ashutosh Nath, Gupta, Amod, Sachdeva, Naresh
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138653/
https://ncbi.nlm.nih.gov/pubmed/30218032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32234-3
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