Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death

Cysteine-rich 61 (Cyr61) belongs to the CCN family and mediates cell proliferation, survival, and apoptosis. Our previous studies showed that Cyr61 protected against hyperoxia-induced lung cell death via Akt phosphorylation. Caveolin-1 (cav-1), a 22-kDa transmembrane scaffolding protein, is the prin...

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Bibliographic Details
Published in:FASEB J
Main Authors: Jin, Yang, Kim, Hong Pyo, Cao, Jiaofei, Zhang, Meng, Ifedigbo, Emeka, Choi, Augustine M. K.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2009
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137882/
https://ncbi.nlm.nih.gov/pubmed/18801924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-108423
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